Syiiergism between Cyclopropenoid Fatty Acids and Chemical Carcinogens in Rainbow Trout (Salmo gairdneri) 1.2
نویسندگان
چکیده
The synergistic activities of cyclopropenoid fatty acids (CPFA), epoxyoleic acid, sesame seed oil, and autoxidized salmon oil with aflatoxin Bt were studied in rainbow trout. Sterculia foetida oil (49% sterculic, 7% malvalic acids) and Hibiscus syriacus oil (2% sterculic and 19% malvalic acids) were used as sources of CPFA. The combination of both 112 and 56 ppm CPFA procured from S, foetida oil and 210 ppm CPFA procured from H. syriacus oil promoted early tumor development, increased tumor incidence, and caused a severalfold increase in tumor growth rate over the positive control. Trout fed 100 ppm 2-acetylaminofluorene for 15 months did not develop hepatomas, but the addition of H. syriacus oil to the diet induced a 20% incidence of liver tumors. Diets containing 200 ppm epoxyoleic acid (in Vernonia anthelmintica oil), 5% sesame seed oil, or 5% autoxidized salmon oil (peroxide value 200-300) did not alter the carcinogenicity of aflatoxin Bj. Some unusual lipid deposits were noted in the livers of fish receiving sesame seed oil.
منابع مشابه
Synergism between cyclopropenoid fatty acids and chemical carcinogens in rainbow trout (Salmo gairdneri).
The synergistic activities of cyclopropenoid fatty acids (CPFA), epoxyoleic acid, sesame seed oil, and autoxidized salmon oil with aflatoxin Bt were studied in rainbow trout. Sterculia foetida oil (49% sterculic, 7% malvalic acids) and Hibiscus syriacus oil (2% sterculic and 19% malvalic acids) were used as sources of CPFA. The combination of both 112 and 56 ppm CPFA procured from S, foetida oi...
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Molecular species composition of the major phospholipids in brain and retina from rainbow trout (Salmo gairdneri). Occurrence of high levels of di-(n-3)polyunsaturated fatty acid species.
The molecular-species compositions of the diacyl classes of the major phospholipids from the brain and retina of rainbow trout (Salmo gairdneri) were determined. A total of 46 possible species was identified. Didocosahexaenoyl species were major components of phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylserine (PS) from retina, comprising 14.1, 41.3 and 28.3% of the r...
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